Improving heart muscle

Identification of Two Main Independent Components of Fibrillating Heart Muscle

Fibrillation is a hazardous phenomenon in cardiac muscle and so any new work towards the understanding of this process is important to the development of new methods in diagnosis and therapy. In this work we have used surface and intra cardiac ECGs of patients with chronic atrial fibrillation (AF). By means of the blind source separation (BSS) algorithm, which is a well-known method in signal p...

Exercise training in chronic heart failure: improving skeletal muscle O2 transport and utilization.

Chronic heart failure (CHF) impairs critical structural and functional components of the O2 transport pathway resulting in exercise intolerance and, consequently, reduced quality of life. In contrast, exercise training is capable of combating many of the CHF-induced impairments and enhancing the matching between skeletal muscle O2 delivery and utilization (Q̇mO2 and V̇mO2 , respectively). The Q̇mO...

HeartBeat--improving heart attack care.

We aimed to save lives by assuring best practice in ST elevation myocardial infarction (STEMI) through initiating the Institute for Healthcare Improvement (IHI) methodology nationally. Following collection of a minimum dataset, annual change in indicators in the five initiating hospitals for the period Oct 2006 - Sept 2009 was assessed by analysing the percentage of patients receiving the eight...

Magnesium in heart muscle.

Muscle cells take heart

JCB • VOLUME 169 • NUMBER 1 • 2005 16 Folding in a crowd roteins fold better in a crowd, as predicted by a biophysical model from Margaret Cheung, Dmitri Klimov, and D. Thirumalai (University of Maryland, College Park, MD). Interactions between a protein and large nearby molecules produce repulsive forces at distances that can be as large as the protein itself. The group modeled the energetic e...